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CGRP inhibitors have had a transformational impact on migraine management since their introduction in 2018, and have been considered first-line treatments since 2024

Pretreatment of mice with either grape seed extract (100 mg/kg/day for 7 days) or green tea extract (0.25% - 1% of diet for 5 days) protected livers from acetaminophen-mediated damage, as determined by serum levels of ALT and microscopic examination (Bagchi 2002